Diagnosis and treatment of recurrent retroperitoneal liposarcoma: An analysis of 37 cases        WU De-quan. Department of General Surgery, the 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
Abstract    Objective    To investigate the clinical characteristics and treatments and key factors of recurrent retroperitoneal liposarcoma（RPLS）. Methods    The clinical data of 37 patients with initial and recurrent RPLS admitted between 2002 and 2012 in the 2nd Affiliated Hospital of Harbin Medical University were analyzed retrospectively．Among 37 patients, there were 13 patients with 22 case-times of postoperative recurrence totally. Results    Compared with initial patients, recurrent patients had the following characteristics：the worse biological behaviors，more likely to lead to clinical symptom, more obvious physical examination positive signs, stronger tumor invasive power, less complete resection and longer time of hospital stays. The interval without tumor burden turned shorter after multiple recurrences，and the survival rate become lower. Conclusion    The characteristics of retroperitoneal space and variousness of tumor’s morphology are important events for recurrence of retroperitoneal liposarcoma. It is the key factor to prevent recurrence and improve prognosis by critical complete and intact resection during the initial process.