Diagnosis and treatment of hyperparathyroid crisis                    SUN Hui, LIU Xiao-li. Department of Thyroid Surgery, China-Japan Union Hospital, Jilin University, Changchun 130033, China
Corresponding author: SUN Hui, E-mail: sunhui1229@163.com
Abstract    Hyperparathyroid crisis induced by hyperparathyroidism is a rare and life-threatening disease, which is most commonly due to a single parathyroid adenoma and is often associated with a characteristic microcystic histopathological pattern.The common manifestations including the marked elevation in PTH and Ca2+，reflect rapid deterioration of cardiac, gastrointestinal, renal, and central nervous function. It also reinforces the importance of preoperative definite diagnostic and accurate lesions localizing, prompt initial medical management and operative timing judgment, frozen section and quickly PTH determination in the operation highlighting the difficulties facing the endocrine surgeon in dealing with parathyroid disease. It is necessary to emphasize perioperative management in treatment of hyperparathyroid crisis. However, urgent surgery is required after the patients are hydrated sufficiently, even if conservative therapy is not successful.