Study of surgical stress on the aged abdominal major operation patients        ZHANG Juan-juan， GAO Tao，XI Feng-chan, et al. Research Institude of General Surgery，Nanjing General Hospital of Nanjing Military Command，PLA，Nanjing 210002，China
Corresponding：YU Wen-kui，E-mail：yudrnj@163.com
Abstact    Objective    To investigate the difference of surgical stress on the aged and non-aged abdominal major operation patients. Methods    From February to April in 2013，a prospective study was performed of abdominal operation patients with gastrointestinal neoplasms in research institude of general surgery, including 36 aged patients (≥65 years old) and 37 non-aged patients (＜65 years old). We observed differences of postoperative vital sign，white blood cell count，neutrophil proportion，C-reactive protein，plasma cortisol and ACTH in two groups，and analyzed these dates. Results    Compared with the non-aged group，plasma cortisol of the first day after operation in aged group was much higher，P=0.049. C-reactive protein of the first day and the second day after operation in aged group was much lower，P(D1)=0.046，P(D2)=0.008. There were no differences of white blood cell count，neutrophil proportion and ACTH in two groups. Conclusion    Compared with the non-aged patients，the stress hormone plasma cortisol of the aged abdominal major operation patients was much higher after operation，but the inflammatory reaction was not higher，and even lower.