Noteworthy issues involving the perioperative sedation and analgesia        LI Qing-dong，WAN Xian-yao. Critical Care Medical Research Institute of Dalian Medical University，Department of Critical Care Medicine，the First Affiliated Hospital of Dalian Medical University，Dalian 116011，China
Corresponding：WAN Xian-yao，E-mail：13322210199@163.com
Abstract    Interventions of preoperative anxiety，assessment and treatment of agitation and pain in critical patients after major operation，sedation and analgesia for postoperative delirium are issues worthy of attention in perioperative period. Preoperative anxiety should not be treated merely by sedatives. Music listening and psychology interview may have more beneficial effect on it. As for critical patients，evaluation-first therapy and analgesia-first sedation should be applied as a strategy. Analgesics and sedatives should be selected based on individualization. It is worth noting that postoperative delirium is easy to be neglected and treated by wrong way.