腹腔镜辅助联合肝脏离断和门静脉结扎二步肝切除术治疗原发性肝癌可行性研究
Chinese Journal of Practical Surgery ›› 2014, Vol. 34 ›› Issue (01) : 77-80.
Laparoscopic-assisted associating liver partition and portal vein ligation for staged hepatectomy for primary liver cancer CAO Jun,ZHANG Hong-wei,ZHANG Lei,et al. Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
Corresponding author:CHEN Ya-jin, E-mail:cyj0509@126.com
Abstract Objective Our aim was to investigate the feasibility of laparoscopic “Associating liver partition and portal vein ligation for staged hepatectomy” (ALPPS) in the treatment of advanced hepatocellular carcinoma. We retrospectively analyzed the clinical data of one patient with a huge right-lobe hepatocellular carcinoma lesion and multiple right-lobe metastases who underwent laparoscopic ALPPS in the Sun Yat-sen Memorial Hospital in August 2013. Methods The first-stage surgery was laparoscopic ligation of the right branch of the portal vein and liver partition. Seven days later, open right hepatic trisegmentectomy was performed as the second-stage surgery. The perioperative indicators were then analyzed. Results The operative time was 205 minutes for the first-stage surgery and 160 minutes for the second-stage surgery. Liver function returned to normal six days after the first-stage surgery and left lateral lobe volume increased 115.9% compared to the preoperative volume. The second-stage open right hepatic trisegmentectomy was then performed safely and liver function returned to normal eight days after the second-stage surgery. Conclusion Laparoscopic ALPPS is an excellent choice for patients with advanced hepatocellular carcinoma and insufficient volume of the future liver remnant.
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