Clinical practice of gene expression tests in bresat cancer          XIN Ling，LIU Qian，XU Ling，et al. Breast Disease Center,Department of General Surgery, Peking University First Hospital, Beijing 100034, China
Corresponding author ：LIU Yin-hua, E-mail：liuyinhua@medmail.com.cn
Abstract    2013 St Gallen Panels recommended gene expression tests in breast  cancer patients, which affirmed the value of multi-gene assays in clinical management among patients with luminal disease. Two available tests, Oncotype Dx TM and MammaPrintTM, have exhibited good metric performance in the prediction of prognosis and treatment benefit of early-stage breast cancer. However, these genomic predictors are still not ready for routine clinical practice for high cost and inaccessible technology in most area. We now focus on the hot issues of gene expressions and  discuss the current status and limitation in clinical practice as follows.