The value of liver functional reserve estimation in large liver cancer anatomic resection        ZHOU Jian, YU Lei.Liver Cancer Institute, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Zhongshan Hospital, Fudan University, Shanghai 200032,China
Corresponding  author ：ZHOU Jian，E-mail: zhou.jian@zs-hospital.sh.cn
Abstract    Liver resection is the main curative treatment for liver tumors. It is susceptible to complicate with postoperative liver failure (PLF) which is a major reason of perioperative death after tumor especially large tumor resection if functional reserve of residual liver is insufficient. Thus, it is important to precise preoperative liver functional reserve estimation to determine if patients tolerate liver resection size to avoid PLF. Currently there are three ways to estimate liver functional reserve before surgery: Dynamic liver function test such as Indocyanine Green Clearance (IGC) test and Monoethylglycinexylidide (MEGX) test; Clinical staging system such as Child-Pugh score; liver volume estimation. Since the recovery of liver function depends on residual liver volume, residual liver quality and the general condition of patients, it’s necessary to combine results from different tests to make the preoperative assessment comprehensive and accurate.