PDF(340 KB)
PDF(340 KB)
PDF(340 KB)
Individualized treatment of pancreatic portal hypertension LOU Wen-hui, LI Jian-ang. Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Corresponding author :LOU Wen-hui,E-mail:lou.wenhui@zs-hospital.sh.cn
Abstract Pancreatic portal hypertension is a clinical syndrome characterized by splenic vein obstruction caused by pancreatic disease. The main clinical manifestation are splenomegaly, gastric varices while no liver function abnormality. Splenic vein obstruction are usually caused by endothelium inflammation and external compression induced by chronic pancreatitis, pancreatic tumor and pseudocyst. The treatment principle should be focus on the primary disease while considering the severity of sinistral portal hypertension. For patients without bleeding, splenectomy is suggested after the surgical treatment of primary pancreatic disease; for bleeding patients, devascularization should be considered. Generally, splenic artery embolism and endoscopic treatment are only considered in the acute setting or the nonoperative candidate
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