Current status and prospects of liver xenotransplantation         DOU Ke-feng*, LI Xiao, TAO Kai-shan, et al. *Department of Hepato-Biliary Surgery and Army institute of organ transplantation, Xijing Hospital, the Forth Military Medical University, Xi’an 710032, China
Corresponding author:Dou Ke-feng, E-mail: doukef@fmmu.edu.cn
Abstract    Procurement of organs from pig can be a novel means to resolve the shortage of donor organs. With the in-depth study of xenograft rejection and zoonotic infectious diseases, the development of a-1,3-galactosyltransferase gene-knockout (GTKO) pigs promote the translation of xenotransplantation from bench to bedside. However, compared with the heart and renal xenotransplantation, the outcome of liver xenotransplantation is still very limited. The longest survival reported was only 14 d. This paper reviews the key issues and possible solutions which may be confronted in the clinical liver xenotransplantation. We hope to provide reference for the further study.