Analysis of related factors of positive results for sentinel lymph node biopsy in patients with early breast cancer          LI Yong-tao，NI Duo，YANG Liang，et al. Department of Breast Surgery, Xinjiang Medical University Cancer Institute and Hospital， Urumqi 830011, China
Corresponding author:ZHU Li-ping, E-mail：doctorzhuliping@yahoo.com.cn
Abstract    Objective    To explore the factors related to early breast cancer patients underwent sentinel lymph node biopsy. Methods    A total of 252 patients with early breast cancer underwent sentinel lymph node biopsy between January 2008 and January 2013 in Xinjiang Medical University Affiliated Tumor Hospital. The clinical pathological characteristics were summarized. The influencing factors of sentinel lymph node biopsy results were analyzed. Results Univariate analysis showed that tumor size，preoperative imaging evaluation,  Her-2，Ki-67， histological grade，molecular typing were correlated with pathologic result of sentinel lymph node biopsy，and the difference was significant statistically. Compared with Lumina type A patients，other early breast cancer molecular subtypes patients underwent sentinel lymph node biopsy were prone to positive results. Multivariate analysis showed that tumor size and Ki-67 expression were correlated with positive results of sentinel lymph node biopsy，and the difference was significant statistically. Conclusion    Preoperative pathological data of early breast cancer patients can predict sentinel lymph node biopsy results，which have certain guidance for further treatment of patients.