Perioperative complication incidence between laparoscopic and open radical resection for advanced gastric cancer: A case control study        LI Ping, HUANG Chang-ming, ZHENG Chao-hui,et a1. Department of Gastric Surgery, Affiliated Union Hospital, Fujian Medical University, Fuzhou 350001, China
Corresponding author: HUANG Chang-ming, E-mail: hcmlr2002@163.com
Abstract    Objective    To compare the surgical complication incidence between laparoscopy-assisted gastrectomy (LAG)  and open gastrectomy (OG) for advanced gastric cancer (AGC) and the related risk factors of postoperative complications  after radical gastrectomy. Methods    A retrospective case-control study was performed comparing LAG and OG for AGC.A total of 148 patients with AGC underwent LAG between January 2010 and December 2011 in Affiliated Union Hospital of Fujian Medical University were enrolled and were compared with 148 AGC patients underwent OG during the same period. The perioperative complication morbidity and mortality were compared between the two groups. The risk factors determined postoperative complications were investigated by univariate and multivariate analysis. Results    The intraoperative complication incidence was 4.1% in LAG group and 4.7% in OG group（P＞0.05）.The postoperative complication incidence was 10.8% in LAG group and 20.9% in OG group（P＜0.05）, among which the complication incidence of postoperative intestinal obstruction was 1.4% and 6.1% in LAG group and in OG group（P＜0.05）,and the complication incidence of postoperative pulmonary infection was 3.4% and 9.5% in LAG group and in OG group（P＜0.05）.There was no significant difference between the two groups in other postoperative complication incidence（P＞0.05）. According to univariate analysis, depth of invasion, lymph node metastasis, operation time and laparoscopic surgery were related to postoperative complications（P＜0.05）. Multivariate logistic regression analysis showed that whether laparoscopic surgery and operation time were independent risk factors for postoperative complications（P＜0.05）. Conclusion    There is no difference in intraoperative complication incidence between LAG and OG groups. But the postoperative complication incidence is significantly lower in LAG group than that in OG group. Whether laparoscopic surgery is an independent risk factor for postoperative complications in advanced gastric cancer.