Factors associated with complication after laparoscopic-assisted radical rectal surgery for rectal cancer                      LIU Lin, WANG Hai-jiang, ZHAO Ze-liang, et al. Department of Gastrointestinal Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China
Corresponding author: WANG Hai-jiang，E-mail：wanghaijiang@medmail.com.cn
Abstract    Objective    To investigate factors associated with postoperative complications after laparoscopic-assisted radical rectal surgery in rectal cancer. Methods    The clinical data of 305 patients with rectal cancer performed laparoscopic-assisted radical resection from April 2008 to April 2012 in Affiliated Tumor Hospital of Xinjiang Medical University were analyzed retrospectively. All the data were analyzed by the t test，chi-square test，Fisher exact probability or Logistic regression model. Results    Postoperative complication occurred in 76 patients (24.9%). On univariate analysis, postoperative complication was associate with gender，age，preoperative comorbidity，location of tumor，TNM staging，neoadjuvant chemoradiotherapy，operative time and surgeon experience（P＜0.05）. Logistic regression analysis revealed that gender，preoperative comorbidity，location of tumor，TNM staging and surgeon experience were independent risk factors for postoperative complications（P＜0.05）. Follow up was available in 275 patients (90.2%) with a median follow up of 24 months（rang，2-48months）. Differences in survival and recurrence rate between patients with and without postoperative complication were of no statistical significance （P >0.05）. Conclusion   Gender，preoperative comorbidity，location of tumor，TNM staging，surgeon experience were independent risk factors for postoperative complications in laparoscopic-assisted radical rectal surgery in rectal cancer.