慢性放射性肠炎合并梗阻病变肠管切除术后早期并发症危险因素分析

Chinese Journal of Practical Surgery ›› 2013, Vol. 33 ›› Issue (07) : 571-575.

Chinese Journal of Practical Surgery ›› 2013, Vol. 33 ›› Issue (07) : 571-575.
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Abstract

Risk factors for early postoperative complication after ileal/ileocecal resection for chronic radiation enteritis with small bowel obstruction        GONG Jian-feng, ZHU Wei-ming, YU Wen-kui, et al. Research Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command PLA, Medical College of Nanjing University, Nanjing 210002, China
Corresponding author :LI Ning, E-mail: liningrigs@yahoo.com.cn
Abstract    Objective    To identify the perioperative complication incidence and its risk factors in patients underwent ileal/ileocecal resection for chronic radiation enteritis (CRE) with small bowel obstruction. Methods    Univariate and multivariate analysis of a retrospectively gathered database between June 2001 and December 2011 in Department of General Surgery, Nanjing General Hospital of Nanjing Military Command PLA were performed on a cohort of patients (n=158) underwent ileal/ileocecal resection for CRE obstruction at a single institution. Altogether, we analyzed 33 potential risk factors to identify significant influence on the postoperative outcome. Results    Overall and major morbidity rates were 57.0% (90 patients) and 28.5% (45 patients), respectively. The mortality rate was 1.9% (3 patients). Univariate analysis determined that ASA score of not less than 3, anemia, low platelet level, long operation time, intraoperative transfusion, presence of radiation uropathy and proctitis and experience of surgeons were important risk factors for Grade Ⅲ-Ⅴ morbidity. Multivariate analysis found ASA score of not less than 3, anemia, intraoperative transfusion, low platelet level, radiation uropathy and surgeon’s experience as independent risk factors for Grade Ⅲ-Ⅴ  morbidity. Conclusion    The current study provides the first evidence of predictive risk factors for postoperative morbidity of ileal/ileocecal resection for CRE.

Key words

radiation enteritis / risk factors / intestinal resection / postoperative complications

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