Diagnosis and therapeutic principle of inflammatory breast cancer        GAO Wei-qi, SHEN Kun-wei. Comprehensive Breast Health Center, Shanghai Ruijin Hospital, Shanghai Jiao Tong University, Shanghai 200025, China
Corresponding author：SHEN Kun-wei，E-mail：kwshen@medmail.com.cn  
Abstract    Inflammatory breast cancer (IBC) is an aggressive manifestation of primary breast cancer that progresses rapidly and carries a very grim prognosis. Diagnosis of IBC is made on the basis of its specific clinical characteristics as well as histopathologic verification of carcinoma. The optimal therapeutic strategy for IBC is to integrate different modalities consisting of neoadjuvant chemotherapy, surgery, radiotherapy, endocrine therapy and targeted therapy. The research of IBC’s molecular pathogenesis might provide potential therapeutic approaches.