Safety of transumbilical single-incision laparoscopic cholecystectomy versus conventional laparoscopic holecystectomy: a meta analysis        WANG Ye-fei*, SHEN Ai , LIU Bo，et al.*Department of Hepatobiliary Surgery，the First Affiliated Hospital of Chongqing Medical University，Chongqing 400016，China
Corresponding author: WANG Hong-lin, E- mail: whlcqykd@163.com
Abstract    Objective    To evaluate the safety of transumbilical single-incision laparoscopic cholecystectomy. Methods Cochrane library (No.1 2011), PubMed (1978-2011), EMBase (1978-2011) and CNKI (1978-2011) were searched for randomized controlled trials on the efficacy of transumbilical single-incision laparoscopic cholecystectomy (SILC) versus conventional laparoscopic holecystectomy (CLC) for the treatment of benign gallbladder disease. According to the inclusion criteria, eight studies were selected. Two authors cited the details about the designs of the trials，identities of the participants and the outcomes from the studies included independently. The data were analyzed by Revman 5.1 software. Results    Operating time in the SILS group was longer than that in the CLC group signi?cantly (weighted mean difference =8.03，95% confidence interval（6.02，10.03），P＜0.01). There was no signi?cant difference in the introoperative blood loss［weighted mean difference=-2.41，95% confidence interval（-5.66，0.83），P=0.15］, postoperative hospital stay［weighted=0.15，95% confidence interval（-0.06，0.37）， P=0.16］ and the postoperative complications incidence［relative risk=1.21， 95% confidence interval（0.53，2.78)，P=0.69］ between the two groups. Conclusion    SILC is a safe procedure for the treatment of uncomplicated gallstone disease, especially for cosmetic purpose.