Etiology of severe acute pancreatitis: an analysis of 337 cases        LU Bo，YANG Hong，QIAN Jia-ming. Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730,China
Corresponding author: QIAN Jia-ming, E-mail: qjiaming57@gmail.com
Abstract    Objective    To analyze the etiology of severe acute pancreatitis (SAP). Methods    The clinical data of 337 cases of SAP hospitalized between January 2000 and December 2011 at Peking Union Medical College（PUMC）Hospital were analyzed retrospectively. Results    Biliary SAP, idiopathic SAP, hyperlipemic SAP and alcoholic SAP was accounted for (46.9%), (19.8%), (16.3%) and (10.4%) respectively. There was an ascending trend in hyperlipemic SAP（10.9% vs. 20.0%, P=0.027）. Male was significantly more than female in alcoholic SAP (15.3% vs. 0.9%, P<0.001). The proportion of biliary SAP in the elderly was higher than that in the non-elderly（74.1% vs. 32.6%, P<0.001). The proportions of hyperlipemic and alcoholic SAP in the non-elderly were higher than those in the elderly（P<0.001）. Conclusion    Biliary factor is the most common etiology of SAP. The proportion of biliary SAP in the elderly is higher than that in non-elderly. With time changed, there is an ascending trend in hyperlipemic SAP. Alcoholic SAP is mainly in male. The cases of hyperlipemic and alcoholic SAP are mainly in the non-elderly.