Some problems of fluid resuscitation in severe acute pancreatitis (type Ⅱ) in 72h of onset        MAO En-qiang*， XU Zhi-wei. *Department of ICU, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Corresponding author: MAO En-qiang，E-mail: maoeq@yeah.net
Abstract    Patients with severe volume deficient in SAP should be treated with controlled fluid resuscitation. Strategies of fluid resuscitation include shortening of histanoxia and prevention of fluid sequestration. The former includes restoration of normal distribution of body fluid and mechanical ventilation as early as possible; the latter includes controlled fluid infused, amelioration of endothelium function and relief of SIRS. Expansion of blood volume, regulation of body fluid distribution and disappearance of SIRS are the major three measures of restoration of normal distribution of body fluid. A positive response included the fulfillment of two or more of four criteria. Complications resulting from fluid resuscitaion treated actively may ameliorate prognosis.