Emphasis on multidisciplinary treatment  of severe acute pancreatitis        WANG Chun-you*, ZHAO Yu-pei. *Pancreatic Disease Research Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022, China
Corresponding author: ZHAO Yu-pei, E-mail: zhao8028@263.net
Abstract    The treatment of severe acute pancreatitis (SAP) has experienced more than a century of exploration. Initially surgery followed by conservative treatment was advocated, and then selective surgical intervention was adopted. Procedures also changed through time, from a simple surgical drainage to pancreatic capsule incision and drainage to pancreatectomy and then necrosectomy. Today, the overall mortality rate of SAP has decreased from 60%~80% to 10%~20%. Therefore, the treatment of SAP include early fluid resuscitation, organ protection and replacement therapy, the treatment of abdominal compartment syndrome, as well as nutritional support, prevention of complications and surgical intervention. Comprehensive prevention and treatment of MODS, infectious complications, as well as accurate timing and approach of surgical intervention should be strengthened to achieve a breakthrough to the effectiveness of SAP management.