Early infection rates of tension-free inguinal hernia repair without prophylactic: a randomized controlled trial          HUANG Yi-jie*，PENG Lin，SHI Zhen-rui,  et al. *Department of Vascular-thyroid-abdominal wall-hernia Surgery, Guangdong Provincial People's Hospital, Guangzhou 510080，China
Corresponding author：PENG Lin，E-mail:pengl@21cn.com
Abstract    Objective    To investigate the feasibility of tension-free repair of inguinal hernia without antibiotic prophylaxis. Methods    According to the principle of randomized controlled trial, a total of 842 cases of adult inguinal hernia treated from July 2010 to July 2011 in Department of Vascular-thyroid-abdominal wall-hernia Surgery，Guangdong Provincial People's Hospital were analyzed prospectively. The cases were divided into two groups (control group and trial group). Cases in trial group (n=200) were treated by antibiotics once preoperatively while cases in control group (n=642) received no antibiotics treatment. The outcomes of early postoperative infection rates between two groups were compared. Results    Among 842 cases, 10 cases (2 from trial group and 8 from control group) developed surgical site infection (SSI). There was no significant difference in the infection rate with 1.0% for trial group vs. 1.2% for control group. No statistical difference was found in the results of complete white blood cell count, neutrophilic granulocyte ratio and hospital stays. Conclusion    There is no real need to apply regular prophylactic antibiotics treatment for adult tension-free repair of inguinal hernia without high risk factors.