Clinical characteristics of gastric cancer patients with pathological complete response following neoadjuvant chemotherapy: an analysis of 11 patients        LI Zi-yu*, YUAN Peng , TANG Lei , et al. *Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China
Corresponding author: JI Jia-fu, E-mail：jiafuj@hotmail.com
Abstract    Objective    To analyze the clinical characteristics of gastric cancer patients with pathological complete response (pCR) following neoadjuvant chemotherapy. Methods    The clinical data of gastric cancer patients who had undergone neoadjuvant chemotherapy from 2001 to 2010 in Peking University Cancer Hospital were collected and eleven patients were found to be pCR with their primary lesion. Results    All the 11 patients were local advanced gastric cancer. Ten of them received the FOLFOX and the other one with SOX as their neoadjuvant regimen. One patient got lymph node metastasis in the pathological examination. The pCR rate of the patients with FOLFOX regimen was lower than 5%, and the accurate rate (2/11) of clinical evaluate method (CT/EUS) was insufficient. All the patients were live without disease, which suggested good prognosis. Conclusion    Based on the pCR, the neoadjuvant chemotherapy regimen and clinical evaluate method await modification.