Diagnosis and treatment of  hepatobiliary cystadenocarcinoma: an analysis of 6 cases        LI Cong, BI Xin-yu, ZHAO Hong, et al. Department of Abdominal Surgery, Cancer Institute Hospital, Chinese Academy of Medical Sciences, Beijing100021, China
Corresponding author: CAI Jian-qiang, E-mail: caijianqiang188@sina.com
Abstract    Objective    To summarize the diagnosis and treatment of hepatobiliary cystadenocarcinoma. Methods    The clinical data of 6 cases of hepatobiliary cystadenocarcinoma received complete excision and confirmed by histopathologic examination between January 1999 and October 2011 in Cancer Institute Hospital, Chinese Academy of Medical Sciences were analyzed retrospectively. Results    Most cases presented with non-specific symptoms. Four cases were with an elevated serum CA19-9 level. One cases of regional lymph nodes metastasis occurred hapatic metastasis 8 months after operation and died 10 months after operation. Another cases sufferred inadequate surgical margin (<5mm) recurred six months after operation and survived for 21 months with chemotherapy. The other 4 cases survived for 9, 10, 38, 108 months respectively. Conclusion    An elevated serum CA19-9 level and imaging examinations may be useful to differentiate hepatobiliary cystadenocarcinoma from other hepatic cystic diseases. Complete excision with negative margin is essential to reduce local recurrence. Regional lymph nodes metastasis may be an important prognostic factor for the disease.