Correlation of serum adiponectin expression with colorectal cancer        CONG Jin-chun, SHEN Ming-yang, FENG Yong, et al. Department of Colorectal Surgery, Shengjing Hospital, China Medical University, Shenyang 110004, China
Corresponding author: FENG Yong, E-mail:fengy@sj-hospital.org
Abstract    Objective    To evaluate the correlation of serum adiponectin expression with favorable clinicopathologic phenotype in colorectal cancer. Methods    Serum adiponectin levels were measured via ABC-ELLSA in 90 cases of colorectal cancer admitted between January 2010 and June 2010 in Shengjing Hospital of China Medical University and 30 normal controls, which were correlated with selected clinicopathological features in colorectal cancer. Results    The levels of adiponectin were significantly lower for colorectal cancers (especially in males)（13.08±7.99μg/mL）than normal controls (21.92±8.76μg/mL)（P<0.01）. With the tumor TNM stages increased, the levels of adiponectin showed decreasing tendency gradually（P<0.05).There was no significant difference for tumor locations and histological types（P >0.05）. Conclusion    Low levels adiponectin in human serum are observed in colorectal cancer. With the tumor TNM stages increased, the levels of adiponectin show the decreased tendency gradually.