Diagnosis and treatment of intrahepatic biliary cystadenoma: an analysis of 17 cases        LIU Yuan, ZHOU Yong, GENG Dong-hua, et al. Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
Corresponding author: LIU Jin-gang, E-mail:liujg@sj-hospital.org
Abstract    Objective    To study the diagnosis and treatment of intrahepatic biliary cystadenoma. Methods    The clinical data of 17 cases of intrahepatic biliary cystadenoma admitted between January 2003 and December 2009 in Shengjing Hospital of China Medical University were analyzed retrospectively. Results    The majority of 17 cases presented as upper abdominal discomfort or pain. Tow cases had undergone previous unroofing of the cyst for misdiagnosis as simple liver cyst. Abnormal serous carbohydrate antigen 19-9 (CA19-9) was observed in 6 cases.  Serous alpha-fetoprotein (AFP) level was slightly elevated in one case, and serous carcinoembryonic antigen (CEA) was normal in all cases. Seven cases were diagnosed correctly according to imaging examination. All the cases underwent total resection of the cyst. Pathological diagnosis was intrahepatic biliary cystadenoma in all the 17 cases, and 3 of them showed malignant change. No recurrence was found after followed up for 8 to 60 months. Conclusion    Preoperative diagnosis of intrahepatic biliary cystadenoma is difficult. Intrahepatic biliary cystadenoma is easy to develop to cystadenocarcinoma. The prognosis of radical resection is satisfied.