Analysis on the evaluation criteria for therapeutic effect of imatinib in GIST        WANG Chun-meng*, SHI Ying-qiang, WU Jiang-hong, et al. *Department of Gastric and Soft Tissue Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Corresponding author: SHI Ying-qiang, E-mail: yingqingshi@126.com
Abstract    Objective    To explore a new evaluation on target therapy in GIST patients. Methods    The clinical data of 4 cases of GIST obtained complete remission after using imatinib between August 2004 and October 2010 at Fudan University Shanghai Cancer Center was analyzed. The imaging by CT or PET-CT scan before operation and pathology results after resection of 4 cases were compared. Results In 4 cases of GIST, 2 cases were evaluated only by imaging ( case 1 was evaluated by both CT and PET-CT), and another 2 cases were evaluated by both imaging and pathology. CT scans of cases performed resection after imatinib therapy was in contradiction of the findings of histopathological examination. Conclusion    The Choi response criteria are superior to the RECIST criteria, and may become the mainstay in the evaluation of imatinib response in GIST cases.