Prognosis of gastrointestinal stromal tumor：a multivariate analysis        FENG Tao*，WANG Yun-hai，XU Xin-cai，et al. *No.2 Department of General Surgery，the Fourth Affiliated Hospital，Xinjiang Medical University，Wulumuqi830000，China
Corresponding author：WANG Yun-hai，E-mail：ftcall777@yahoo.com.cn
Abstract    Objective    To explore the clinical characteristics as prognostic factors in patients with gastrointestinal stromal tumors (GISTs).  Methods    The clinical and pathological data of 75 patients with GISTs admitted between February 2002 and October 2008 at the First and Fourth Affiliated Hospital of Xin Jiang Medical University were analyzed retrospectively. All the patients were followed up. COX Proportional Hazard Model was used in multivariate analysis. Results    GISTs occurred more frequently in middle-aged patients and most of them were located in the gaster. Age, gender, nationality, preoperative discomfort, preoperative symptoms and preoperative anemia were not statistically different from prognosis (P>0.05）. The diameter of the tumor, surgery, during the invasion and metastasis, staging, grading, the transfer of recurrence significantly（P<0.05）. The diameter of the tumor, intraoperative invasion and metastasis were independent prognostic factors affecting prognosis of patients based on a multivariate analysis of COX Proportional Hazard Model. Conclusion    Tumor diameter, intraoperative invasion and metastasis are important factors affecting the prognosis of patients with GIST. The tumor sites, operation methods, staging, grading, recurrence and metastasis are also the evaluation indexes of prognosis. Completive surgical excision is still an effective treatment.