Role of aggressive surgical approach for gallbladder carcinoma with special consideration of the extent of radical resection        YU Wen-long,YANG Xiao-yu,ZHANG Yong-jie. Biliary Tract Surgery DepartmentⅡ, Eastern Hepatobilillary Surgery Hospital, the Second Military Medical University,  Shanghai200438,China
Corresponding author:ZHANG Yong-jie, E-mail:yjoy005@sina.com
Abstract    Currently, radical resection remains the only way to cure gallbladder carcinoma. Because of the high invasion of gallbladder carcinoma, an effort to improve the extent of surgical resection thus becomes the inevitable choice. However, the risk associated with the extended radical resection of gallbladder carcinoma is still high, and the prognosis of patients with gallbladder carcinoma treated in its advanced stage is still not satisfactory even with extensive radical surgery. With assuring operation safety as the premise, extensive radical resection of gallbladder carcinoma should should be performed in an attempt to achieve an R0 resection. To develop an individualized surgical plan, the following factors should be considered:  foci of the size, location and relative to neighboring organs, growth pattern of tumour and whether lymphatic and vascular invasion. The patient's physical conditions, surgeon’s skills and medical condition of hospital should be taken into account also.