New understanding and treatment principle of precancerosis of gallbladder carcinoma        ZHAO Gang, WU Zhi-yong. Department of General Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
Corresponding author: WU Zhi-yong, E-mail:zhiyongwu@gmail.com
Abstract    Gallbladder carcinoma is the most common carcinoma of biliary tract and has high degree of malignancy. Most of the clinical diagnosis is in the late stage, because gallbladder carcinoma has low rate of preoperative diagnosis. The overall prognosis is poor. Now the cause is not clear. Dysplasia of gallbladder mucosa and gallbladder adenoma are recognized as precancerosis of gallbladder carcinoma. And some benign gallbladder diseases such as cholecystitis, gallstones, polypoid lesions of the gallbladder and anomalous junction of the pancreaticobiliary duct gradually may evolve into precancerosis of gallbladder carcinoma by the process of pathophysiology，then develop into gallbladder carcinoma. Therefore, It should pay more attention to precancerosis of gallbladder carcinoma and choose a reasonable time of surgery to improve the survival rate.