Nutrition regulation therapy in metabolism，immunity and organ function of critical ill patients: current thinking and future directions        LI Ning.  Research Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command, Najing  210002， China
Abstract    Critical ill patients who undergoing hypercatabolism, immunity inflammatory reaction disordered and organ dysfunction, could not be improved by exclusively nutriment supply. Current conception of clinical nutritional support in the intensive care unit (ICU) has been evolved. The purpose that used to be filling cellular metabolic need including enough energy and nutrition elements for metabolism，has now expanded into modifying inflammation and hypercatabolism，improving immune and endocrine status, and protecting organ function. And, it is the change from ‘nutritional support’ to ‘nutritional therapy’. Recent investigations of nutrition support in the ICU have relatively conformed regulation of stress atabolism and promotion anabolic in clinical practice. Following pharmacology and immunology nutrition developed, the current conception and content of nutrition regulation therapy have new expanded from ‘nutrition support’. For critical ill patients, it is necessary to familiar with the changes of metabolism, immunity inflammatory reaction and organ-function of patients. At the right moment, to adopt reasonable, active and immunity regulation therapy has hopeful to amend and protect organ-function of patients. The regulation therapy of metabolism and immunity makes an important ingredient in the combined therapy strategy of critical ill patients.