Targeted therapy of gallbladder carcinoma        LIU Ying-bin*, WU Wen-guang, QUAN Zhi-wei. *Xinhua Hospital, Shanghai Jiaotong University，Shanghai 200092, China
Corresponding  author: LIU Ying-bin，E-mail: laoniulyb@163.com
Abstract    Primary carcinoma of the gallbladder (PCG) is the most common malignant tumor in biliary system and its morbility has been rising year by year in our country. Because there is no specific clinical manifestation, patients diagnosed finally as PCG has mostly been in intermediate or advanced stage, thus losing the chance of radical resection of gallbladder carcinoma and having a poor prognosis. Improved understanding of the molecular carcinogenesis of adenocarcinomas of the gallbladder, coupled with the availability of novel molecularly targeted chemotherapeutic agents, may improve outcome for patients. Targeted therapy has gradually developed to become a new therapy and displays favourable prospect of application.