Effect analysis of laparoscopic radical resection for colorectal cancer        XING Jia-di*, CUI Ming, MA Yi-yuan, et al. *Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of Minimally Invasive Gastrointestinal Surgery，Peking University School of Oncology，Beijing Cancer Hospital & Institute, Beijing 100142, China
Corresponding author: SU Xiang-qian, E-mail: suxiangqian@gmail.com
Abstract    Objective    To evaluate the feasibility of laparoscopic radical resection and open procedures for colorectal cancer. Methods    Twenty-nine patients with colorectal cancer were performed laparoscopic radical resection between June 2006 and January 2007 at the Department of Minimally Invasive Gastrointestinal Surgery of Beijing Cancer Hospital. It selected 30 patients who underwent open radical resection in the same period with the same diseases retrospectively, compared the radical effect, operation time, intra and post-operative complications, time of bowel function rehabilitation, post-operative hospital stay, 30-day mortality, 2 years’disease free survival and overall survival. Results    Both groups obeyed the surgical principle of colorectal cancer including extent of resection and bowel margins. Significant differences were shown between laparoscopic and open surgery groups in operation time, intra-operative hemorrhage, time of bowel function rehabilitation and post-operative hospital stay. There was no differences between the two groups in other intra and post-operative complications, lymph nodes harvested, 30-day mortality, 2 years’overall survival and disease free survival. Conclusion    Laparoscopic radical resection can be a proper choice for curable colorectal cancer, which can get the same radical effect and short-term outcome comparing with open procedure. Besides, laparoscopic surgery provides advantages in intra-operative hemorrhage, time of bowel function rehabilitation and post-operative hospital stay, but do not give patients apparent extra burden during and after the operation, although it may take longer time in the duration of operation. The long-term prognosis of laparoscopic surgery need to be confirmed in further follow-up.