Clinical research of effects of nutrition support containing differential fatty acids ingredient on improving protein catabolism of liver transplantation patients        ZHOU Xü, LIU Jun, YANG Feng-hui, et al. Center of Organ Transplantation, Provincial Hospital Affiliated to Shandong University, Jinan 250021,China
Corresponding author: LIU Jun, E-mail:zhouxu2008@sina.com
Abstract    Objective    To compare the difference of effects between enteral nutrition and parenteral nutrition formula containing either MCT/LCT or LCT only on protein metabolism of liver transplantation(LTP) patients and determine the mechanism of MCT/LCT improving nutritional status of LTP patients. Methods    A random controlled clinical trail containing 86 cases of liver transplantation was conducted and all the cases were divided into 4 groups.  The several parameters were observed before liver transplantation 1day and after liver transplantation 1, 4, 7 and 10 days, such as serum concentrations of transferrin and prealbumin. Results    The results showed that the patients of F, N group had an increased blood concentration of transferrin, prealbumin than those of the patients of K, C group( P<0.05 or P<0.01). The above two parameters were markedly higher in group F than in group N as same as group K vs group C(P<0.05 or P<0.01). Excretion of nitrogen and 3-methylhistidine in urine was also markedly reduced in patients fed with nutrients containing MCT/LCT compared with LCT(P<0.05 or P<0.01) . Nitrogen balance was better in group F than that in N and K group. Conclusion    An enteral compound diet containing MCT/LCT can reduce decomposition of the body proteins, enhance the level of serum albumin, and improve the status of protein metabolism of patients after liver transplantation more effectively.