Association of gallbladder carcinoma and anomalous pancreaticobiliary ductal junction  TIAN Fu-zhou, LUO Zhu-lin, ZHANG Bing-yin，et al. PLA General Surgery Center, Chengdu General Military Hospital, Chengdu 610083, China
Corresponding author: TIAN Fu-zhou, E-mail: tfz30061@yahoo.com.cn
Abstract    Incidence of gallbladder carcinoma in patient with anomalous pancreaticobiliary ductal junction （APBD）has been noted as high as 50% or more. The patients with APBD have an earlier age of onset comparing with the “normal people”. It found the similar result in 694 pancreaticobiliary ductal image materials admitted between 1995—2007 at PLA General Surgery Center of Chengdu General Military Hospital. Incidence of gallbladder carcinoma in patients with APBD was 21.8%. It is noteworthy that the length of common channel (CC) more than 15 mm is considered as the gold standard for the diagnosis of APBD in the world. The literature about characteristics of gallbladder carcinoma in “normal people” with the length of CC less than 15mm is rare. All the “normal people” were divided into short CC group and long CC group except for 28 patients with APBD in 694 pancreaticobiliary ductal image materials. Incidence of the latter was 10 times higher than that of the former. The concentration of amylase in bile in long CC group was higher than that in short CC group. The mechanism of the high incidence of gallbladder carcinoma may the reflux of the pancreatic juice into the bile duct. Measuring the length of CC and detecting the concentration of amylase in bile might be a method for predicting the onset risk of gallbladder carcinoma.