Hypothermia, acidosis and coagulopathy    GONG Jian-feng，ZHU Wei-ming . Research Institute of General Surgery，Clinical School of Medicine, Nanjing University, Nanjing General Hospital of Nanjing Military Command，PLA，Nanjing 210002，China
Corresponding author：ZHU Wei-ming，E-mail：juwiming@yahoo.com.cn
Abstract    Coagulopathy is a life threatening complication in trauma patients who have sustained significant injuries and blood loss. Its association with hypothermia and metabolic acidosis is common and constitutes a vicious cycle, causing a “lethal triad”. The most important treatment of hypocoagulability is the avoidance or rapid reversal of the lethal triad, which has been the theoretical basis for the application of damage control surgery (DCS) and damage control resuscitation (DCR) techniques in patients with severe trauma.