Perioperative management of massive blood transfusion with dysfunction of blood coagulation in hepatopancreatobiliary surgery        JIN Hao-sheng，OU Jin-rui. Department of Hepatopancreatobiliary Surgery, Guangdong General Hospital , Guangdong Academy of Medical Sciences, Guangzhou 510080 , China
Corresponding  author：OU Jin-rui ，E-mail: oujinrui@yahoo.com.cn
Abstract    Objective    To summarize the experience in perioperative management of massive blood transfusion with dysfunction of blood coagulation in hepatopancreatobiliary surgery.  Methods    The clinical data of 11 cases underwent massive blood transfusion with dysfunction of blood coagulation in hepatopancreatobiliary surgery from January 2006 to July 2009 at the Department of Hepatopancrea to biliary Surgery of Guangdong General Hospital were analyzed retrospectively. Results    Through individualized, comprehensive and gradually infusion of various types of blood clotting substances, the appropriate surgical treatment and other relevant measures, 10 cases of dysfunction of blood coagulation were corrected; one case of splenectomy, porto-azygos devascularization and cholecystectomy died of wide range of portal vein thrombosis.  Conclusion    It should correctly judge the main reason of massive blood transfusion with dysfunction of blood coagulation in hepatopancreatobiliary surgery, rationally use of various types of blood clotting substances and choose the appropriate surgical treatment and other relevant measures.