Strategy of fluid resuscitation in septic shock patients JIN De-xi, CAO Li-ping. Department of Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou310009, China Corresponding author: CAO Li-ping, E-mail: cao@zju.edu.cn Abstract The mortality of septic shock remains between 30% and 60%, which is the 10th leading cause of death in the ICU. Fluid resuscitation is necessary and most important for the restoration. Furthermore，early fluid resuscitation is considered as the central of “bundle therapy”.