Surgical manipulation of major blood vessels invaded by retroperitoneal tumors TIAN Wen. Department of General Surgery, General Hopistal of PLA ,Beijing 100853 ,China E-mail：tianwen301@sina.com Abstract When the retroperitoneal tumor patients with clinic symptoms seek medical treatment，the tumors are usually large and involve major blood vessels. The correct surgical manipulation of major blood vessels invaded by retroperitoneal tumors is important to raise the resection rate.The examination of CT, MRI and DSA（digital subtration angiography）can help preoperative evaluation and preparation for major blood vessels resection and reconstruction. Good vessel exposing plays a necessary part in vessel resection and reconstruction. Before controling bleeding and vessel reconstruction, local or systemic heparinization should be necessary. Some important vessels need to repair and reconstruction. Now using autologous blood vessels for vessel reconstruction has been more common, artificial blood vessels and mesh greatly facilitate reconstruction. It should be paid attention to vascular function reconstruction, preventing postoperative vascular injury and thrombosis.