Application of binding local inflow occlusion in laparoscopic hepatectomy ZHEN Zuo-jun,WANG Feng-jie.Department of Hepatobiliary Surgery ,the First People’s Hospital of Foshan,Foshan 528000,China Corresponding author:ZHEN Zuo-jun, E-mail: docterwfj@sina.com Abstract Objective To evaluate the feasibility and efficacy of binding local inflow occlusion in laparoscopic hepatectomy for hepatocellular carcinoma (HCC). Methods A retrospective comparative study for laparoscopic liver resection for HCC in the segments of Ⅱ and Ⅲ using either the Pringle maneuver (group A,14 cases) or the binding local inflow occlusion method (group B,12 cases) were initiated in Department of Hepatobiliary Surgery of the First People’s Hospital of Foshan between March 2004 and October 2008. The intraoperative blood loss, postoperative alanine aminotransferase (ALT) and total bilirubin (TBIL), the medina hospital stay between the two groups were analyzed. Results No differences in the intraoperative blood loss were found between the two groups(P>0.05). The ALT were significantly elevated in group A when compared with group B, group B patients also had significantly faster recovery of liver function(P<0.01). No differences in TBIL were found between the two groups(P>0.05).The medina hospital stay for group B were significantly shorter than group A(P<0.01). Conclusion Binding local inflow occlusion in laparoscopic hepatectomy was feasible, effectively blocked local inflow and decreased the damage to remnant liver, especially was suit for patients with cirrhosis liver disease.