Significance of measurement of serum tumor markers in differential diagnosis of mass lesion on pancreatic head LIAO Quan,ZHAO Yu-pei. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medial Sciences, Beijing 100730, China Corresponding author:ZHAO Yu-pei, E-mail:zhao8028@263.net Abstract The conclusion showed that the single measurement of serum tumor markers can not satisfy the clinical need of differential diagnosis of mass lesion on pancreatic head. Combined with the many other examinations of medical imageology and cytology, the accuracy rate of differential diagnosis can be raised. At the same times , we should continue to find the new serum tumor markers in order to increase the diagnosis and prognosis capability of mass lesion on pancreatic head.