Cholelithiasis complicated with cholangiocarcinoma DOU Ke-feng, AN Jia-ze. Department of Hepatobilliary Surgery，Xijing Hospital, the Fourth Military Medical University，Xi'an 710032，China Corresponding author: DOU Ke-feng, E-mail：gdwk@fmmu.edu.cn Abstract The occurrence of intrahepatic cholangiocarcinoma was closely related to the biliary tract long-term recurrent infection and bile duct endothelial chronic injury. Its general shape can be divided into the tumor type, nodular type, papillary type and diffuse sclerosis type. Tubular adenocarcinoma was main histological type. Hepatolithiasis with hepatic cholangiocarcinoma exist high misdiagnosis rate, low early diagnosis rate, B ultrasound and CT enhance inspection are most commonly used and with higher value. Radical resection of the liver is the preferred method of treatment, liver transplantation is an effective treatment measure. The prognosis of this disease is poor.