Management of tertiary peritonitis Ren Jian-an Li Jie-shou. Rsearch Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command of PLA, Nanjing 210002, China Corresponding author: REN Jian-an, E-mail: jian@medmail.com.cn Abstract Through understanding of the etiology and pathology of peritonitis physiological characteristics, it can prevent the third type of peritonitis. In order to prevent the third type of peritonitis, the surgeon should diagnose and treat primary and secondary peritonitis timely, pay attention to the source of infection and control operation as well as the rational use of drugs. To strengthen the monitoring and regulating immune function, and carry out enteral nutrition support actively, including timely and rational operation and drainage is most important.