Hepatic ollicular dentritic cell sarcoma: a case report and review of the literature LIU Jun，ZHANG Zhong-tao，LI Jian-she, et al. Department of General Surgery, Beijng Friendship Hospital, Capital Medical University, Beijing 100050,China Corresponding author: ZHANG Zhong-tao , E-mail: zhangzht@medmail.com.cn Abstract Objective To explore the hepatic follicular dendritic cell sarcoma (FDCS) of the histopathological and immunohistochemical characteristics. Methods One case of hepatic FDCS was diagnosed and treated in June 2008 at Beijng Friendship Hospital of Capital Medical University. Histopathological and immunohistochemical characteristics of hepatic FDCS and related literature review were analyzed and summarized. Results The hepatic FDCS hadn’t special symptoms nor characterized imaging features, and was difficult to make correct diagnosis before operation. A large single mass in liver was showed in CT scan. Microscopically, the neoplastic cells were in ovoid or spindle and some of them had indistinct cell borders. Neoplastic cells were positive for CD35, but negative for CD21, CD23, S-100, ALK, EBER in immunohistochemical analysis. Conclusion The FDCS is a rare low-grade malignant tumor. Its diagnosis should mainly rely on histopathological and immunohistochemical findings. Complete excision is the main therapeutic method for it.