Clinical application of Sentinel lymph node biopsy technology in gastric cancer and it′s micrometastasis detection YOU Jian-Quan*，MA Li-lin .*Department of General Surgery, Taizhou People’s Hospital,Taizhou 225300, China Abstract Objective To investigate the micrometastasis of sentinel lymph node and the feasibility of sentinel lymph node biopsy in gastric cancer. Methods Sixty patients with gastric cancer intraoperatvely underwent setinel lymph node biopsy with methylene. All SLNs were studied with HE and FCM (Flow cytometry) technique,respectively. ResuLts The stained SLNs couLd be identified in 56(93.3%) of 60 patients. 49 SLNs were found to have lymph node metastases in 23 patients by HE, however, 71 SLNs were found to have lymph node metastases in 27 patients by FCM.That is to say: 22 SLNs micrometastases were detected in 13 patients. In the patients with gastric cancer of T1 and T2 groups, SLN can much more accurately predict the LNs status. Conclusion Intraoperatvely SLNB with methylene in gastric cancer is more feasible in T1 and T2 groups; FCM binding SLNB can detect lymph node micrometastasis in gastric cancer as many as possible that is feasible and prospective.