Liver transplantation in treatment of complicated biliary injury YAN Ji-qi, PENG Cheng- hong, YANG Wei-ping, et al. Department of Surgery, Ruijin Hospital, Medical School of Shanghai Jiaotong University， Shanghai 200025, China. Corresponding author： PENG Cheng-hong, E-mail:chhpeng@188.com Abstract Objective To investigate liver transplantation in treatment of failed cases after surgical interventions for bile duct injury. Methods From November 2006 to May 2007, two cases of failed cases after surgical interventions for bile duct injury were admitted into our hospital. These clinical data were analyzed retrospectively. Results Bile duct injury (Strasberg E4) in one patient was caused by laparoscopic cholecystectomy concomitant with proper hepatic artery lesion, after the failure of previous Roux-en-Y hepaticojejunostomy, the patient received corpse liver transplantation. Bile duct injury (Strasberg E2) in another patient was caused by abdominal trauma in childhood, after several unsuccessful surgical interventions, the patient developed secondary biliary cirrhosis, and therefore, received living related liver transplantation. The outcome of both patients was satisfactory. Conclusion Liver transplantation should be considered when bile duct injury happens concomitant with severe vascular injury or secondary biliary cirrhosis occurs after failure of surgical intervention.