Hepatectomy with selective total hemihepatic vascular occlusion TONG Ying， XU Feng，KAN Tong，et al . Department of Special Treatment， Eastern Hepatobiliary Surgery Hospital，the Second Military Medical University， Shanghai 200438， China Corresponding author：YANG Jia-mei，E-mail：lilytongy@hotmail.com Abstract Objective To explore the preliminary clinical evaluation of hepatectomy with selective total hemihepatic vascular occlusion. Methods One hundred patients with primary liver cancer that underwent regular hepatectomy not exceeding half liver in Special Treatment Department of Eastern Hepatobiliary Surgery Hospital between 2006 and 2007 were retrospectively analyzed. Thirty-five patients of them received hepatectomy with total hemihepatic vascular occlusion (group A). The other sixty-five patients received hepatectomy with total hepatic inflow occlusion (group B). The time of hepatic vascular control，intraoperative blood loss，blood transfusion, volume of removed liver，postoperative liver function recovery and complications were compared between the two groups. Results The intraoperative blood loss and blood transfusion in group A were less significantly than that in group B (P <0.05). The serum pre-albumin levels on the day 3 and 7 after operation in group A were higher significantly than that in group B (P <0.05), while the time of hepatic vascular control in group A was longer significantly than that in group B and the volume of lost liver were no difference between the groups(P＞0.05). The serum alanine aminotransferase levels on the day 1,3 and 7 after operation in group A were lower significantly than that in group B(P＜0.01). The incidence rates of postoperative complications were no difference significantly(P＞0.05). Conclusion Intraoperative blood loss during hepatectomy under the selective total hemihepatic vascular occlusion could be less and liver damage could be abated.