Clinical research of two kinds of open operation in herniorrhaphy with artificial synthetic material for parastomal hernias SHEN Ying-mo, CHEN Jie. Center of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital, Capital University of Medical Science, Beijing 100020, China Abstract Objective To evaluate the effect of two kinds of open operation in herniorrhaphy with artificial synthetic material for parastomal hernias by the application with the method of IPOM or Onlay respectively. Methods The clinical data of 48 patients with parastomal hernia admitted from January 2002 to July 2007 at Beijing Chaoyang Hospital of Capital University of Medical Science were analyzed retrospectively. Twenty-five patients received Bard CK parastomal patch repair (IPOM group). Twenty-three patients received Bard Marlex mesh repair (Onlay group). Data collected included operation time, days of postoperative stay, the cases of postoperative complications. The data were analyzed by statistical method. Results No significant difference was found between the two groups in the operation time and the days of postoperative stay. During the follow up period of 6～72 months, there was no recurrence but there were 2 cases of wound infection, 2 cases of subcutaneous seroma and 3 cases of postoperative chronic pain or foreign body sensation in the IPOM group. There were 5 cases of recurrence, 4 cases of wound infection, 6 cases of subcutaneous seroma and 9 cases of postoperative chronic pain or foreign body sensation in the Onlay group. The incidence of recurrence and postoperative chronic pain or foreign body sensation in the IPOM group were lower than those in the Onlay group significantly (P<0.05). Conclusion The two kinds of open operation in herniorrhaphy with artificial synthetic material for parastomal hernias are safe and effective surgical procedures. The method of IPOM can diminish the incidence of recurrence and postoperative chronic pain or foreign body sensation, and diminish the incidence of postoperative wound infection and subcutaneous seroma.