Assessment of energy expenditure and body composition in cancer patientsCAO Dongxing,ZHANG Bo,ZHENG Liewei,et al.Department of General Surgery,Zhongshan Hospital，Fudan University，Shanghai 200032，China Corresponding author:WU Guohao,Email：wugh@zshospital.net AbstractObjectiveTo assess the alternations of resting energy expenditure,fuel utilization, and body composition in cancer patients, and to establish if there is a relationship between REE and fuel utilization.MethodsREE,CO and FO of 714 cancer patients and 642 control subjects admitted between September 2006 and March 2008 at Zhongshan Hospital of Fudan University were measured by indirect calorimetry.ECF,ICF and TW were measured by bioelectrical impedance appliance,and FM,FFM were further determined.ResultsCompared with the controls, cancer patients showed higher mREE/FFM and mREE/PEE.They were at a higher energy consumption status.Cancer patients showed higher FO,lower CO and npRQ,higher ECF,lower ICF,higher TW/BW and ECF/BW,lower ICF/BW.Cancer patients exhibited lower FM,FM/BW and FFM,higher FFM/BW,and lower BCM.ConclusionCancer patients exhibit a wide energy distribution and have elevated energy expenditure in general.Cancer type, pathological stage and duration of disease are potentially important determinants of REE.Cancer patients had increased FO,decreased CO and npRQ,which is correlative with the elevated REE.FM and FFM lose in parallel in cancer patients.BCM diminishes in cancer patients.Increased TW/BW and ECF/BW,decreased ICF/BW is found in cancer patients.