Application of localization needles under fiberoptic ductoscopy to the operation of intraductal space occupying lesions without palpable massYUAN Zhu,QU Xiang,ZHANG Zhongtao,et al.Department of General Surgery,Beijing Friendship Hospital Affiliated to Capital University of Medical Sciences,Beijing 100050,China Corresponding author：ZHANG Zhongtao,Email:zhangzht@medmail.com.cn AbstractObjectiveTo evaluate the value of localization needles under fiberoptic ductoscopy (FDS) for localizing intraductal space occupying lesions without palpable mass.MethodsNintytwo patients with nipple discharge accepted 117 cases of fiberoptic ductoscopy examination from August 2006 to March 2008 at Beijing Friendship Hospital. By the localization needles system under FDS,the intraductal space occupying lesions with unpalpable mass in 24 patients were localized and excised. FDS diagnosis,operation and pathologic diagnosis were analyzed retrospectively.ResultsTwenty-one of 24 patients with intraductal space occupying lesions were pathologically diagnosed (875%).Intraductal papilloma and galactocele were found in 16 patients and 2 patients respectively.Intraductal cancer and invasive duct cancer were found in 2 patients and 1 patient respectively.ConclusionApplication of localization needles under FDS can detect intraductal space occupying lesions early and locate accurate site,which is favorable to improve the diagnosis of early breast cancer and successful rate of operation.