Objective:o evaluate the safety and efficacy of compression anastomosis clip (CAC) for small bowel anastomosis. Methods:rom January 2006 to March 2007,30 gastric cancer patients performed total gastrectomy in the Department of Surgical Oncology of First Hospital Affiliated to Fujian Medical University were randomly divided into two groups and received sidetoside Roux-en-Y small bowel anastomosis with CAC or stapler.The following parameters were recorded,small bowel anastomotic complication,first postoperation flatus and bowel movement,extrusion of clip device. Results:Neither group had small bowel anastomotic complications such as leakage or obstruction.The clip was expelled with stool within 7-14 days．Two groups had the similar results in recovery of bowel function． Conclusion:CAC is safe and simple for small bowel anastomosis.