Objective:To summarize the nutritional supporting experiences in anastomotic leakage following esophagogastrostomy or esophagojejunostomy after gastrectomy for gastric carcinoma and to increase the level of treatment of anastomotic leakage following esophagogastrostomy or esophagojejunostomy. Methods:A total of 19 cases of anastomotic leakage following esophagogastrostomy (6 cases) or esophagojejunostomy (13 cases) after gastrectomy for gastric carcinoma in PLA General Hospital from January 1997 to December 2006 were analyzed retrospectively. Results:All of the cases were treated with abdominal cavity drainage,continuous gastrointestinal decompression and parenteral nutrition combined with enteral nutrition.Sixteen cases were given glutamine enrichment.Ninteen cases were infused somatostatin.Five cases were supplemented recombinant human growth hormone.Four cases′ fistula had been healed after gastrectomy for gastric carcinoma 21～30d.Twelve cases′ fistula had been healed 30～60d.Two cases′ fistula had been healed 60～81d.One case complicated with severe sepsis of thoracic cavity,lung and abdominal cavity died 42d after gastrectomy for gastric carcinoma. Conclusion:The treatment with abdominal cavity drainage,continuous gastrointestinal decompression,parenteral nutrition combined with enteral nutrition,glutamine,somatostatin and recombinant human growth hormone are the important factors for healing of anastomotic leakage following esophagogastrostomy or esophagojejunostomy after gastrectomy for gastric carcinoma.