Objective:To evaluate the clinical value of the Sanya Criteria in the treatment of liver transplantation for hepatocellular carcinoma. Methods:Seventyfive patients who had underwent OLT for hepatocellular carcinoma from April 2003 to January 2006 in the Eastern Hepatobiliary Srugery Hospital were retrospectively analyzed.The matching degree of the Sanya Criteria and other criteria for liver transplantation was studied. Results:The 1,2,3year overall survival rates of the total 75 patients after operation were 85%,74% and 67%,respectively and the recurrencefree survival rates were 80%,74% and 66%,respectively.The data in the Sanya Group were 92%,88%,74% and 92%,88%,72%,respectively.There was no significant difference between Sanya Criteria and the other criteria with regard to the postOLT survival rates. Conclusion:The SanYa Criteria is an efficient screening standard. The SanYa Criteria and the UCSF Criteria may be more applicable to the screening for liver transplantation in patients suffering from hepatocellular carcinoma